Top 5 Probiotics of 2021

Probiotic Bottles
Probiotic Bottles

Our Greatest Defense

The single largest part of the human immune system is the microbiome along our gastrointestinal tract which is home to around 100 trillion microorganisms. Those trillions of good bacteria, known as ‘probiotics’,  make up over 70% of our immune system.

But our microbiome is constantly under attack. Stress, pollution, lack of sleep, and the countless antibiotics and preservatives in all of the foods we eat – all of these things starve and kill off the healthy probiotics in our bodies.

However, as humans discovered over 10,000 years ago – these probiotics can be replenished. Ancient Egyptians fermented milk to make yogurts and cheeses which were said to have staved off stomach problems. In The Bible, Abraham offered to God, ‘fermented milk’.

In modern times, we have more effective methods of replenishing probiotics – namely with probiotic capsules. As probiotics ideally need to be delivered to the intestinal tract, they are uniquely suited to being an oral supplement if they are in an enteric-coated capsule.

Unlike other supplements, such as multivitamins or healthy oils, probiotics do not need to be absorbed into the bloodstream to work. That is why probiotics may be the only type of supplement which actually produces significant, reliable results – some of which are:

Did You Know That Not All Probiotics Work?

There is, however, more to formulating an effective probiotic than throwing some strains in a capsule.

For example: A probiotic which does not include an organic simple starch, which some call a ‘prebiotic’, almost ensures that the probiotics will have starved to death before reaching you. Including a prebiotic also greatly increases the odds that the probiotic strains in the product will establish a successful colony – one that will be able to sustain itself over time.

Keep track of time: Effective probiotics will noticeably begin working within days. Usually you will notice an increase in natural energy and digestive regularity first, with healthy weight changes within two weeks.

With so many brands of probiotics on the market, how can you find the right one? Because every product claims to be the “most effective“, it can be hard to find the probiotic that best suits your particular needs. Luckily, that’s what we’re here for.

Firstly, this list will ONLY include probiotics which are manufactured in accordance with cGMP guidelines.

If a probiotic was NOT manufactured in clean, regulated conditions, as per cGMP guidelines then in all likelihood it will not only be ineffective but it could be POTENTIALLY HAZARDOUS!

There are 3 factors which impact our grade of each probiotic. They are listed and explained below.

Potency – WAY too many companies leave their probiotics sitting around gathering dust, over 50% of the brands that we tested had ZERO live cultures left! Potency is the % of live cultures we discovered upon testing the brand, you’d be surprised at how many companies store their probiotics for way too long.

CFU (Colony-Forming Units) – this is the total count of all of the bacteria in the probiotic, VERY important because probiotics are ONLY EFFECTIVE IN ADEQUATE AMOUNTS.

Strains – total number of different types of bacteria in each probiotic, varies greatly and, along with strain diversity, affects the types and levels of benefits that you will notice.

- Editor's Choice 2021 -

BlueBiotics Ultimate Care Probiotics Bottle
Viable Cultures
99%
Ingredients
95%
Strain Diversity
94%
Customer Satisfaction
97%
Return Policy
96%

Pros

Cons

Here’s Why:

  • 61 Billion live probiotics per serving (CFU)
  • 11 proven strains, only top proven strains are included
  • Endorsed by many doctors and health professionals
  • Contains S. Boulardii – possibly the most effective, but most expensive, probiotic strain. Many companies do not include S. Boulardii because of the cost
  • Small Capsules Designed to resist stomach acid – a must for any probiotic to be effective
  • Vegetarian capsules + free of potentially hazardous binders and fillers
  • Highest % of living cultures among top brands tested – by far

From Lactobacillus acidophilus to Bacillus Coagulans, the BlueBiotics blend is a veritable list of the most researched and proven probiotic bacteria known to science. And recent advances on the blend have made it the only full-spectrum probiotic supplement on the market, as it contains strains which are typically not available to the general public (Bacillus Coagulans and S. boulardii). The CFU count alone is remarkable enough, leaving most comparable spectrums in the dust… HOWEVER even more surprisingly our tests showed that a whopping 98% of the probiotic colonies in BlueBiotics were still alive, making this BY FAR the most effective probiotic supplement that we have ever reviewed. Also, because of the diverse pool of strains in BlueBiotics, users have reported a wide variety of benefits from weight loss, to increased energy, improved digestive health and cognitive function. Many of our staff switched to these probiotics, as well as myself and my family.

BlueBiotics capsules are also free from unnatural additives, contain a resistant-starch which serves as a food and fuel for the probiotic strains, and are enteric-coated to protect the strains which aren’t acid-resistant from being destroyed by your stomach acids.

Read Full Review >>

2. Ultimate Flora

by RenewLife

ultimate flora probiotics
Viable Cultures
87%
Ingredients
81%
Strain Diversity
88%
Customer Satisfaction
86%
Return Policy
92%

Pros

Cons

Here’s Why:

  • 50 Billion live probiotics per serving (CFU)
  • 10 top strains, many proven strains are included
  • Capsules Designed to resist stomach acid
  • Vegetarian capsules + free of potentially hazardous binders and fillers
  • High % of living cultures

Ultimate Flora tested significantly higher than the majority of general probiotic blends. This product is composed of very well-documented probiotic strains and is an effective addition to any lifestyle, capable of conferring a wide variety of health benefits. The probiotic strains are not only diverse, they were also resilient to outside influences and, in many cases, were successful in establishing colonies within the digestive tracts of study participants.

Despite the hefty CFU advertised by Ultimate Flora, a large portion of the probiotic colonies were no longer alive upon analysis. This resulted in the effective CFU being much lower than what was claimed by the product.

Read Full Review >>

3. RAW Probiotics

by Garden of Life

Viable Cultures
68%
Ingredients
73%
Strain Diversity
92%
Customer Satisfaction
78%
Return Policy
87%

Pros

Cons

Here’s Why:

  • Produced by a trusted, well known brand
  • 100 Billion CFU
  • 34 Strains
  • Vegetarian capsules + free of potentially hazardous binders and fillers
  • Reasonably high % of living cultures

Topping the probiotic market numbers at 100 Billion CFU divided between 34 probiotic strains, Garden of Life’s Ultimate Care probiotic was definitely a contender for best probiotic. Free from preservatives and additives, RAW scored impressive marks across the board. Although this shortens the lifespan of the probiotics strains somewhat, buying in small quantities can easily solve this problem and – honestly – at CHR we always prefer purity to additives.

We were a little disappointed to see that this product was not enteric-coated. Although enteric-coating is not necessary for roughly 70% of the cultures in this probiotic, the remaining 30% (probiotics such as Streptococcus Thermophilus) will be devastated by your stomach acids. That is the only real drawback for an otherwise exemplary probiotic.

Read Full Review >>

4. Multi-Strain Probiotic

by Innovix Labs

innovix probiotics
Viable Cultures
82%
Ingredients
67%
Strain Diversity
73%
Customer Satisfaction
77%
Return Policy
82%

Pros

Cons

Here’s Why:

  • 31 Strains
  • 50 Billion CFU
  • Capsules Designed to resist stomach acid
  • High % of living cultures

The 13 strains in this probiotic include complete lactobacillus and bifidobacterium complexes, as well as two variants of the Streptococcus Thermophilus bacterium. Additionally, this supplement features enteric-coated capsules ensuring that your stomach acids won’t eat up the probiotics before they get to your intestines.

The only reason InnovixLabs didn’t outrank a couple other probiotics on this list was due to its worrying amounts of additives, including: Microcrystalline Cellulose, Hydroxypropyl Methylcellulose, and Silicon Dioxide.

Read Full Review >>

5. PRO-25

by Vitamin Bounty

Pro-25 Probiotics
Viable Cultures
68%
Ingredients
66%
Strain Diversity
71%
Customer Satisfaction
66%
Return Policy
81%

Pros

Cons

Here’s Why:

  • Produced by a trusted, well known brand
  • 25 Billion CFU
  • 13 Proven Strains
  • Designed to resist stomach acid
  • Very high % of living cultures

Vitamin Bounty’s probiotic contains a variety of well-studied strains and a competitive 25 Billion CFU. It also contains a natural prebiotic resistant starch, rice flour, to fuel the strains this probiotic supplies. Over 95% of Pro 25’s strains were still active and viable, the second highest observed strain viability out of all probiotics reviewed-to-date!

This product does contain the magnesium stearate additive, and the CFU/Strain count is a little under the recommended levels, however those are only a couple negative marks on an otherwise incredible product!

Read Full Review >>
 

Want to learn more about probiotics? Take a look at our guide to understanding probiotics here.

The Final Verdict

There are so many probiotic products on the market- it can be overwhelming, but the one that consistently stands above the rest is BlueBiotics: Ultimate Care by BlueBiology.

Their formula is superior to anything else available on the market and what’s listed on the label is actually in the product. Many of the products we tested did not have as many living cultures as advertised but BlueBiotics: Ultimate Care lived up to its raving reviews.

Congratulations to BlueBiology for formulating and producing the best probiotic product on the market!

You can find BlueBiotics: Ultimate Care on BlueBiology’s website.

217 thoughts on “Top 5 Probiotics of 2021”

  1. Hi Julia,

    My husband had his abdominal aorta replaced last August of 2018. The doctor has him on Amoxcillan 850mg 1 x a day. The doctor has recommended he take a probiotic each day due to the antibiotic is to destroy bad bacteria. There are so many out there it is difficult to determine which one would be best for him. Any ideas where we could start?

    Thank you

    Reply
  2. I recently purchased the Garden of Life Raw brand and was wondering if that many live cultures could trigger diarrhea. There seemed to be correlation, but I wasn’t sure. Thoughts?

    Reply
  3. Hi Julia, I have had a J pouch for 29 years and I will get pouchitis quite a bit. I was wondering if you know what would be the best probiotic to use for this issue.

    Reply
    • Hi Dan, we generally recommend BlueBiotics Ultimate Care because it’s a broad-spectrum probiotic. It contains 11 strains so you have a better shot at improving specific conditions like yours because each probiotic strains has its own unique health benefits.

      Reply
  4. I was wondering if you reviewed Best Naturals probiotics 30 billion CFU?

    I have been taking these probiotics either an hour or two before breakfast—is this ok?

    I have Parkinson’s disease and I have read that a lot of diseases start with the gut. I am trying to improve my gut flora/microbiome. Do you think I should change brands?

    Reply
    • Hi Monica, taking probiotics an hour or two before breakfast is probably fine as long as it doesn’t upset your stomach. Although some studies indicate that taking probiotics with a meal results in better survivability of the probiotics.

      If that product works for you, then, by all means, stick with it. You really can’t go wrong with any of the products listed here if you decide to try something else.

      Reply

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