Top Five Sleep Aids

This is where you will find only the brands which passed our lab’s quality analysis. Our quality analysis, which is our basic supplement screening process, simply filters product that do not meet the following criteria:

  • The supplement must contain at least 95% of the ingredient quantity claimed by its label (5% deterioration is the standard allowance for storage and delivery)
  • The supplement must contain NO IMPURITIES OR ADDITIVES

After the screening process, each product is graded according to additional criteria:

  • Variety – an effective sleep supplement needs to have three different ingredients, each of which attacks different threats to our sleep.
  • Supplement diversity – there are various different herbal and other natural supplements included, such as: valerian root, chamomile extract, melatonin, and many others.
  • Potency – the amount of active ingredients within the supplement.
  • Price – self-explanatory, however it is important to remember that in most cases you get what you pay for.
Image of a chart comparing the best sleep supplements

         #1 NeuroScience Serene

                         – Editors Choice –

by NeuroScience

NeuroScience is a privately-owned professional grade dietary supplement company specializing in proprietary blends of amino acids that support better brain function. We love this company because all of their products are backed by scientific evidence by design and their quality manufacturing is top-notch.

The primary active ingredient of this supplement is 5-HTP, a serotonin precursor. This is designed to ensure that your body has what it needs to create sufficient levels of serotonin, a neurotransmitter (chemical) which regulates mood and the sleep-wake cycle. In addition, Serene contains folate and vitamin B6 which are strongly linked to mood and sleep quality. Due to very positive consumer feedback and effective amounts of key nutrients, NeuroScience Serene has earned the title of our Best Sleep Supplement of 2019, 2020 & 2021.

Overall Score: 4.7/5

Variety: 5 high-quality supplement ingredients — Vitamin C, Vitamin B6, Folate, Calcium & 5-HTP

Supplement Diversity: 4.5/5

Potency: 4.8/5

Key Features 

  • Product formula is backed by research and science 
  • cGMP manufactured in the United States 
  • 3rd-Party tested for quality and potency 
  • Safe, non-habit forming ingredients

          #2 Nested Naturals Luna Natural Sleep Aid

by Nested Naturals

Luna is a wonderful, natural herbal sleep supplement which contains a wide variety of calming extracts and amino acids. We love this supplement because the formula is scientifically-based but also includes well-known herbal ingredients that people have been using for hundreds of years. These include valerian extract, chamomile extract and more. Luna Herbal Sleep Aid is specifically geared towards reducing anxiety and morning grogginess, the blend of chamomile extract, valerian root, and passionflower is highly effective. This supplement also works well for dissipating stress. It is also melatonin-free, which is preferable as melatonin can cause you to feel lethargic upon waking up.

Overall Score: 4.6/5

Variety: 6 high-quality supplement ingredients — Valerian Extract, Passionflower Extract, L-Theanine, Chamomile Extract, Hops Extract, Lemon balm Extract

Supplement Diversity: 4.8/5

Potency: 4.0/5

Key Features 

  • Product formula is backed by research and science 
  • cGMP manufactured in the United States 
  • Includes herbal remedies
  • Safe, non-habit forming ingredients

         #3 Physician’s  Choice  Natural  Sleep  Aid

by Physician’s Choice

Another 100% natural option is Physician’s Choice Sleep Aid. The primary active ingredient Suntheanine is a patented and specially tailored form of the amino acid L-Theanine – an amino acid which is found almost exclusively in tea.

Physician’s Choice is a reputable company with a solid background in health supplements. Consumers loved this product of theirs in particular, as feedback has been overwhelmingly positive. This supplement contains many key-ingredients such as Vitamin B6, chamomile, valerian root, melatonin and more – but is less potent than its competitors. It is still a fantastic, high-quality supplement that is loved by most consumers and a great choice for a sleep aid. 

Overall Score: 4.4/5

Variety: 5 high-quality supplement ingredients — Vitamin B6, Chamomile Flowers, Valerian Root, L-Theanine, Melatonin

Supplement Diversity: 4.8/5

Potency: 4.0/5

Key Features 

  • cGMP manufactured in the United States 
  • Includes herbal remedies
  • Safe, non-habit forming ingredients
  • Patented ingredients reviewed by healthcare experts & physicians
  • Contains melatonin instead of a precursor to melatonin such as 5-HTP

          #4 Nuvana Shut  Eye

by Nuvana

#4 on our list is Nuvana Shut Eye. This product prides itself on being neurologist formulated using all-natural ingredients. This is also a non-habit forming product that will not leave you feeling groggy in the morning. 

This product formulation takes a different design than the previously listed products. It contains a combination of naturally sourced ingredients such as Valerian Root Extract, Passion Flower Extract and Lemon Balm Aerial and combines it with ingredients like GABA (gamma-Aminobutyric acid) and Magnesium. Receiving an impressive average of 4/5 stars on its thousands of amazon ratings — consumers clearly love this product. There is less scientific evidence behind some of the ingredients in this product (such as Lemon Balm Aerial) but it’s clear this product is effective for many people. It is #4 on our list because it does indeed contain the listed ingredients scoring high for supplement potency and consumer approval. 

Overall Score: 4.3/5

Variety: 9 high-quality supplement ingredients

Supplement Diversity: 4.2/5

Potency: 4.4/5

Key Features

  • cGMP manufactured in the United States 
  • Includes herbal remedies
  • Safe, non-habit forming ingredients
  • Formulated by neurologists
  • designed to help improve sleep quantity and quality

         #5 Puritan’s Pride Super Snooze With Melatonin

by Puritan’s Pride

Puritan’s Pride has been in business for over 45 years and is known for producing high-quality products. This sleep supplement is an affordable option that checks out in potency. It takes a more simplistic approach to solving life’s great mystery to a better nights sleep. It is very simple and contains one ingredient: Melatonin. Simply replacing melatonin is a cost-effective remedy that works for millions of people. It’s a method that is tried and true for most people but no everyone. The price (varying from place to place) is pretty unbeatable so you really can’t go wrong trying it out to see if simple, pure melatonin is the key to a better night’s sleep for you or your loved ones. 

Overall Score: 4/5

Variety: 1 high-quality supplement ingredients

Supplement Diversity: 3/5

Potency: 5/5

Key Features

  • cGMP manufactured in the United States 
  • Simple and effective for most people
  • Safe, non-habit forming ingredient: Melatonin

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