This is where you will find only the brands which passed our lab’s quality analysis. Our quality analysis, which is our basic supplement screening process, simply filters product that do not meet the following criteria:

  • The supplement must contain at least 95% of the ingredient quantity claimed by its label (5% deterioration is the standard allowance for storage and delivery)
  • The supplement must contain NO IMPURITIES OR ADDITIVES

After the screening process, each product is graded according to additional criteria:

  • Variety – an effective sleep supplement needs to have three different ingredients, each of which attacks different threats to our sleep.
  • Supplement diversity – there are various different herbal and other natural supplements included, such as: valerian root, chamomile extract, melatonin, and many others.
  • Potency – the amount of active ingredients within the supplement.
  • Price – self-explanatory, however it is important to remember that in most cases you get what you pay for.
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Image of a chart comparing the best sleep supplements

         #1 NeuroScience  Serene


Neuroscience is a solid company with a great track record of producing quality cognitive health supplements.

The primary active ingredient of this supplement is 5-HTP, a serotonin precursor. This is designed to ensure that your body has what it needs to create sufficient levels of serotonin, a neurotransmitter (chemical) which regulates mood and the sleep-wake cycle.

In addition, Serene contains folate and vitamin B6 which are strongly linked to mood and sleep quality.

Due to very positive consumer feedback and effective amounts of key nutrients, Neuroscience Serene has earned the title of Best Sleep Supplement of 2019.

Overall Score: 4.7/5

Variety: 4 high-quality supplement ingredients

Supplement Diversity: 4.5/5

Potency: 4.8/5

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          #2 Nested  Naturals  Luna  Natural  Sleep  Aid71yGsS1GftL._SY679_

Nested Naturals

Luna is a wonderful, natural herbal sleep supplement which contains a wide variety of calming extracts and amino acids.

More specifically geared towards reducing anxiety and morning grogginess, the blend of chamomile extract, valerian root, and passionflower is highly effective. This supplement also works well for dissipating stress. It is also melatonin-free, which is preferable as melatonin can cause you to feel lethargic upon waking up.

Overall Score: 4.6/5

Variety: 8 high-quality supplement ingredients

Supplement Diversity: 4.8/5

Potency: 4.0/5

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         #3 Physician’s  Choice  Natural  Sleep  Aid

Overall Score: 4.4/5

Another 100% natural option is Physician’s Choice Sleep Aid. The primary active ingredient Suntheanine is a patented and specially tailored form of the amino acid L-Theanine – an amino acid which is found almost exclusively in tea.

Physician’s Choice is a reputable company with a solid background in health supplements. Consumers loved this product of theirs in particular, as feedback has been overwhelmingly positive.

Variety: 8 high-quality supplement ingredients

Supplement Diversity: 4.8/5

Potency: 4.0/5

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          #4 Nuvana  Shut  Eye

Overall Score: 4.3/5

Variety: 9 high-quality supplement ingredients

Supplement Diversity: 4.2/5

Potency: 4.4/5

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         #5 Puritan’s Pride Super Snooze With Melatonin

Overall Score: 4.1/5

Variety: 8 high-quality supplement ingredients

Supplement Diversity: 4.8/5

Potency: 4.0/5

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